Why are fat-soluble vitamins (A, D, E, K) generally associated with a higher risk of toxicity (hypervitaminosis) compared to water-soluble vitamins?

Options:

• A: Fat-soluble vitamins are rapidly degraded into toxic metabolites in the bloodstream.
• B: They act as direct transcription factors, causing immediate cellular damage.
• C: They bypass the liver filtration system and enter the lymphatic system directly.
• D: They are stored in significant quantities in the liver and adipose tissues and are not easily excreted in urine.

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