Arrange the following events in the development of mitotic mosaicism (e.g., mosaic Down syndrome) starting from a normal diploid zygote:\n1. Normal mitotic divisions producing diploid cells.\n2. Non-disjunction of chromosome 21 during an early embryonic mitotic division.\n3. Generation of two distinct cell lines: one trisomic (47, +21) and one monosomic (45, -21).\n4. Elimination of the monosomic cell line and survival of both normal (46) and trisomic (47) cell lines.\nSelect the correct sequence using the codes given below:

Options:

  • A: 2-1-3-4
  • B: 1-3-2-4
  • C: 2-3-1-4
  • D: 1-2-3-4

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