Given below are two statements, one labeled as Assertion (A) and the other labeled as Reason (R). **Assertion (A):** Chronic obesity and elevated levels of free fatty acids (FFAs) are strongly linked to the development of insulin resistance in skeletal muscle and liver. **Reason (R):** Intracellular accumulation of lipid metabolites (like diacylglycerol) activates serine/threonine kinases that phosphorylate insulin receptor substrate-1 (IRS-1), disrupting insulin signaling. In the context of the above statements, which of the following is correct?

Options:

• A: Both A and R are true but R is not the correct explanation of A
• B: A is true but R is false
• C: Both A and R are true and R is the correct explanation of A
• D: A is false but R is true

Related Practice Questions:

• Let $S_1$ and $S_2$ be two disjoint, non-empty convex sets in $\mathbb{R}^n$. Under which of the following conditions is there guaranteed to exist a hyperplane that strictly separates $S_1$ and $S_2$?
• Let the primal linear programming problem be: Maximize $Z = c^T x$ subject to $Ax \le b, x \ge 0$. If this primal problem has an unbounded optimal objective value, then which of the following statements is always true regarding its dual problem?
• Let $S = \{(x, y) \in \mathbb{R}^2 \mid x^2 + y^2 \le 9\}$ be a convex set in $\mathbb{R}^2$. The set of all extreme points of $S$ is given by:
• In a linear programming problem with $3$ independent equality constraints and $5$ variables (including slack/surplus variables), what is the maximum possible number of basic solutions?