The spindle assembly checkpoint (SAC) monitors the correct attachment of spindle microtubules to kinetochores. If a cell has even a single unattached kinetochore during metaphase, which of the following downstream events is directly prevented from occurring?

Options:

• A: Condensation of chromosomes by condensin complexes.
• B: Activation of the Anaphase-Promoting Complex/Cyclosome (APC/C) and subsequent degradation of securin.
• C: Dissolution of the nuclear membrane by phosphorylation of lamins.
• D: Synthesis of cyclin B during the G2 phase.

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