Trypanosoma brucei, the causative agent of African Sleeping Sickness, can evade the host's immune system indefinitely. Which of the following biological mechanisms explains this ability?

Options:

  • A: Continuous alteration of its Variant Surface Glycoproteins (VSGs) through gene switching.
  • B: Intracellular replication inside the host's mature erythrocytes, hiding from antibodies.
  • C: Secretion of enzymes that specifically degrade host immunoglobulins (IgG and IgM).
  • D: Formation of highly resistant calcified cysts in the host's skeletal muscles.

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