If a person's blood glucose level exceeds the renal threshold (approximately 180 mg/dL), glucose begins to appear in the urine (glucosuria). What is the primary physiological reason for this phenomenon?

Options:

  • A: The glomerular filtration membrane becomes damaged and allows larger molecules to pass.
  • B: The active transport symporters (SGLT) in the proximal convoluted tubule become completely saturated.
  • C: The loop of Henle actively secretes excess glucose into the tubular lumen.
  • D: Insulin deficiency prevents the cells of the collecting duct from absorbing glucose.

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