Arrange the following milestones in the structural elucidation and synthesis of Penicillin in the correct chronological order (from earliest to latest): 1. Discovery of Penicillin by Alexander Fleming 2. Determination of the beta-lactam structure of Penicillin by Dorothy Hodgkin using X-ray crystallography 3. First total chemical synthesis of Penicillin V by John C. Sheehan 4. Introduction of Ampicillin, the first semi-synthetic broad-spectrum penicillin

Options:

  • A: 2-1-3-4
  • B: 1-3-2-4
  • C: 1-2-4-3
  • D: 1-2-3-4

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