Arrange the following stages in the pathogenesis of Typhoid fever in the correct sequential order, starting from the ingestion of the pathogen: 1. Invasion of Peyer's patches in the distal ileum of the small intestine. 2. Entry into the bloodstream causing transient primary bacteremia. 3. Ingestion of contaminated food or water containing Salmonella Typhi. 4. Multiplication of bacteria within macrophages of the reticuloendothelial system (liver, spleen, and bone marrow). 5. Secondary bacteremia leading to sustained high fever, abdominal pain, and clinical symptoms. Select the correct sequence:

Options:

  • A: 3 - 2 - 1 - 4 - 5
  • B: 1 - 3 - 2 - 4 - 5
  • C: 3 - 1 - 4 - 2 - 5
  • D: 3 - 1 - 2 - 4 - 5

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