Consider the following statements regarding the processes of Somatic Hypermutation (SHM) and Class Switch Recombination (CSR) in B-lymphocytes: 1. Class Switch Recombination changes the constant region of the heavy chain (CH) but preserves the antigen-binding specificity of the variable region. 2. Somatic Hypermutation occurs in the germinal centers of secondary lymphoid organs and increases the affinity of antibodies for the antigen. 3. Both class switching and somatic hypermutation are initiated by the enzyme Activation-Induced Cytidine Deaminase (AID). Which of the statements given above are correct?

Options:

• A: 1 and 2 only
• B: 2 and 3 only
• C: 1, 2 and 3
• D: 1 and 3 only

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