Arrange the following events in the hypothalamic-pituitary-adrenal (HPA) axis in the correct sequence starting from the perception of a stressor: 1. Release of Adrenocorticotropic Hormone (ACTH) from the anterior pituitary. 2. Secretion of Corticotropin-Releasing Hormone (CRH) from the hypothalamus. 3. Release of Cortisol from the adrenal cortex into the systemic circulation. 4. Binding of ACTH to receptors on the cells of the zona fasciculata. Select the correct sequence from the options below:

Options:

• A: 1-2-4-3
• B: 2-1-4-3
• C: 2-4-1-3
• D: 1-4-2-3

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