Oligomycin is a toxic antibiotic that binds specifically to the Fo subunit of ATP synthase in mitochondria. What is the immediate biochemical consequence of treating cells with Oligomycin?

Options:

• A: It directly blocks the transfer of electrons from Complex I to Ubiquinone, halting the proton pump.
• B: It increases the permeability of the inner mitochondrial membrane to protons, dissipating the proton gradient.
• C: It blocks the flow of protons through the Fo channel, stopping ATP synthesis and eventually halting the electron transport chain due to proton accumulation in the intermembrane space.
• D: It physically disrupts the outer mitochondrial membrane, causing the leakage of Cytochrome c into the cytosol.

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