Arrange the following events of a primary humoral immune response in the correct sequential order from initiation to antibody secretion: 1. Antigen binding to the B-cell receptor (BCR). 2. Receptor-mediated endocytosis and presentation of antigen on MHC Class II molecules. 3. Helper T-cell (Th) binding via TCR and CD4, releasing cytokines. 4. Clonal expansion and differentiation of B cells into plasma cells. 5. Secretion of antigen-specific antibodies. Select the correct sequence:

Options:

• A: 2-1-3-5-4
• B: 1-3-2-4-5
• C: 1-2-3-4-5
• D: 3-1-2-4-5

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